{"id":7860,"date":"2023-07-14T16:42:32","date_gmt":"2023-07-14T14:42:32","guid":{"rendered":"http:\/\/www.frederic-poitou.com\/blog\/?p=7860"},"modified":"2026-04-21T14:18:55","modified_gmt":"2026-04-21T12:18:55","slug":"les-sels-de-nicotine","status":"publish","type":"post","link":"https:\/\/www.frederic-poitou.com\/blog\/les-sels-de-nicotine\/","title":{"rendered":"LES SELS DE NICOTINE"},"content":{"rendered":"

Les sels de nicotine connaissent un succ\u00e8s public grandissant, par l\u2019effet qu\u2019ils produisent dans les e-liquides dans lesquels ils sont incorpor\u00e9s. Cependant, on trouve sous la d\u00e9nomination \u00ab\u00a0sels de nicotine\u00a0\u00bb des r\u00e9alit\u00e9s tr\u00e8s diff\u00e9rentes. Cette mise au point ne traite que le cas des trois sels de nicotine les plus courants (benzoate, l\u00e9vulinate et lactate), mais la probl\u00e9matique reste identique pour les autres sels de nicotine du march\u00e9 (citrate, pyruvate, malate, succinate), plus rarement utilis\u00e9s.<\/p>\n

Pr\u00e9paration et r\u00e9alit\u00e9 chimique <\/b><\/h3>\n

Un sel est obtenu en associant un acide et une base par liaison ionique.<\/p>\n

Pour faire simple, une liaison ionique ressemble \u00e0 l\u2019attraction de deux aimants l\u2019un vers l\u2019autre. Les cristaux qui en sont issus sont g\u00e9n\u00e9ralement solubles dans l\u2019eau, sensibles au pH et \u00e0 l\u2019\u00e9lectron\u00e9gativit\u00e9 (puisque leur association est de type \u00e9lectrostatique). Le liquide ainsi obtenu traverse, dans un premier temps, une r\u00e9sistance o\u00f9 il subit une influence \u00e9lectrostatique, puis l\u2019environnement buccal dont le pH est alcalin.<\/p>\n

Il existe des sels min\u00e9raux qui associent des m\u00e9taux et des min\u00e9raux, comme le sel de table et des sels organiques qui associent des mol\u00e9cules carbon\u00e9es et oxyg\u00e8n\u00e9es, comme dans le cas qui nous int\u00e9resse ici.<\/p>\n

 <\/p>\n

Etape 1 : Obtention des cristaux<\/i><\/strong><\/p>\n

En m\u00e9langeant les deux compos\u00e9s dans des conditions tr\u00e8s pr\u00e9cises d\u2019acidit\u00e9 (pH), de temp\u00e9rature, mais surtout de proportion relative et apr\u00e8s \u00e9vaporation du solvant, les deux mol\u00e9cules se lient de mani\u00e8re stable. Un sel de nicotine n\u2019est pas un liquide, mais un cristal, de point de fusion de l\u2019ordre de 18,7\u00b0C qui contient les proportions d\u2019acides et de nicotine suivantes, selon le sel consid\u00e9r\u00e9 :<\/p>\n

Benzoate de nicotine : 57,05% de nicotine et 42,95% d\u2019acide benzo\u00efque.<\/p>\n

Salicylate de nicotine : 54,02% de nicotine et 46,01% d\u2019acide salicylique.<\/p>\n

L\u00e9vulinate de nicotine : 58,29% de nicotine et 41,71% d\u2019acide l\u00e9vunique<\/p>\n

C\u2019est sous cette forme de cristal, dont la puret\u00e9 doit \u00eatre syst\u00e9matiquement contr\u00f4l\u00e9e, et dont nous avons un t\u00e9moin pur au laboratoire, que le produit est vendu aux fabricants. Un proc\u00e9d\u00e9 bien maitris\u00e9 conduit \u00e0 des cristaux d\u2019une puret\u00e9 sup\u00e9rieure \u00e0 99,8%, alors qu\u2019un m\u00e9canisme r\u00e9actionnel approximatif conduit \u00e0 la pr\u00e9sence d\u2019acide ou de nicotine libres qui rendent le produit fini potentiellement dangereux.<\/p>\n

Etape 2 : Dilution<\/i><\/strong><\/p>\n

L\u2019interm\u00e9diaire suivant dilue les cristaux dans un m\u00e9lange PG\/VG puis les revend aux formulateurs.<\/p>\n

Apr\u00e8s analyses, on constate au laboratoire que moins de 20% des \u00e9chantillons analys\u00e9s sont conformes aux indications des fiches techniques et d\u2019\u00e9tiquetage. Dans le meilleur des cas, les concentrations sont plus faibles qu\u2019annonc\u00e9es, dans le pire elles sont totalement fantaisistes si bien que le formulateur ne conna\u00eet pas le taux de nicotine du produit fini qu\u2019il propose aux consommateurs avant mise sur le march\u00e9, ce qui peut lui poser un vrai probl\u00e8me d\u2019\u00e9tiquetage.<\/p>\n

Il convient de noter que les organismes fran\u00e7ais et europ\u00e9ens comp\u00e9tents (l\u2019ANSES, DGCCRF et EFAS) ne consid\u00e8rent que le taux r\u00e9el de nicotine libre contenu dans le produit fini selon la l\u00e9gislation existante.<\/p>\n

Avantages et inconv\u00e9nients des sels par rapport \u00e0 la nicotine libre.
\n<\/b><\/h3>\n

<\/h3>\n

Lire la suite<\/a><\/strong><\/b><\/p>\n","protected":false},"excerpt":{"rendered":"

Les sels de nicotine connaissent un succ\u00e8s public grandissant, par l\u2019effet qu\u2019ils produisent dans les e-liquides dans lesquels ils sont incorpor\u00e9s. Cependant, on trouve sous la d\u00e9nomination \u00ab\u00a0sels de nicotine\u00a0\u00bb des r\u00e9alit\u00e9s tr\u00e8s diff\u00e9rentes. Cette mise au point ne traite … Lire la suite\u00ad\u00ad<\/a><\/p>\n","protected":false},"author":4,"featured_media":7862,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"kt_blocks_editor_width":"","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[48],"tags":[],"class_list":["post-7860","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-accueil"],"yoast_head":"\nLES SELS DE NICOTINE -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.frederic-poitou.com\/blog\/les-sels-de-nicotine\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"LES SELS DE NICOTINE -\" \/>\n<meta property=\"og:description\" content=\"Les sels de nicotine connaissent un succ\u00e8s public grandissant, par l\u2019effet qu\u2019ils produisent dans les e-liquides dans lesquels ils sont incorpor\u00e9s. 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